Article
Impact of matrix metalloproteinase-8 gene variations on the risk of thoracic aortic dissection in a Chinese Han population.
Molecular biology reports - 1 Oct 2013
Wang Xiao-Zeng, Du Xiao-Mo, Jing Quan-Min, Li Xing-Xing, Gu Ruo-Xi, Wang Jiao, Han Ya-Ling
Abstract excerpt
The importance of matrix metalloproteinase 8 (MMP8) expression during the progression of thoracic aortic dissection (TAD) has been recently emphasized. Genetic variations that affect proteinase expression or activity might contribute to the pathogenesis of TAD. In this study, we investigated whether the MMP8 C-799T genotype is associated with TAD. The frequency distributions of the MMP8 C-799T polymorphism were...
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