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Article

Association of TNF-α gene variations with thoracic aortic dissection risk in a Chinese Han population.

International angiology : a journal of the International Union of Angiology - 1 Aug 2016

DU Xiao M, Liu Li W, DU Zhan K, Gu Ruo X, Han Ya L, Wang Xiao Z

Abstract excerpt

BACKGROUND: Chronic inflammation may be involved in pathogenesis of thoracic aortic dissection (TAD). Tumor necrosis factor-alpha (TNF-α) is a proinflammatory cytokine that plays an important role in pathological TAD progression. In this study, we determined wether genetic variants of TNF-α were associated with TAD. METHODS: Frequency distributions of TNF-α promoter polymorphisms (-1031C/T,-857C/T,-308G/A, and...

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Share to Aortic Aneurysm, Thoracic
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PMID: 26544637

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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