Article
Association between -799C/T single nucleotide polymorphism of the MMP‑8 promoter region and thoracic aortic dissection.
Molecular medicine reports - 1 Oct 2014
Li Yun, Li Na, Ma Wei, Jiang Yuanzhu, Ma Guoyuan, Zhang Lin
Abstract excerpt
Thoracic aortic dissection (TAD) is a life-threatening vascular condition, in which matrix metalloproteinases (MMPs) are involved. Since the key determinants underlying MMP action remain elusive, the present study investigated the correlation between single nucleotide polymorphisms (SNPs) in the promoter region of the MMP‑8 gene and a predisposition to TAD, by comparing genotypes of TAD patients and healthy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
