Article
Association of Toll-Like Receptor 4 Gene Polymorphisms with Acute Aortic Dissection in a Chinese Han Population.
BioMed research international - 1 Jan 2020
Li Tan, Liu Xiaozheng, Ning Hongxia, Li Xintong, Yang Jun, Ma Chunyan
Abstract excerpt
BACKGROUND: Inflammation may be involved in the pathogenesis of acute aortic dissection (AAD). Toll-like receptor 4 (TLR4) is known to play a critical role in regulating the immune and inflammatory processes. To date, the relationship between genetic variation of TLR4 and AAD is far from clear. The purpose of our study was to illustrate the relevance of TLR4 polymorphisms with the susceptibility to AAD. METHODS:...
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