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Article

Integrated analysis of DNA methylation and mutations in esophageal squamous cell carcinoma.

Molecular carcinogenesis - 1 Dec 2016

Kishino Takayoshi, Niwa Tohru, Yamashita Satoshi, Takahashi Takamasa, Nakazato Hidetsugu, Nakajima Takeshi, Igaki Hiroyasu, Tachimori Yuji, Suzuki Yasuyuki, Ushijima Toshikazu

Abstract excerpt

The recent development of next-generation sequencing technology for extensive mutation analysis, and beadarray technology for genome-wide DNA methylation analysis has made it possible to obtain integrated pictures of genetic and epigenetic alterations, using the same cancer samples. In this study, we aimed to characterize such a picture in esophageal squamous cell carcinomas (ESCCs). Base substitutions of 55...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26756304
DOI: 10.1002/mc.22452

Genes

CHFR
SFRP1
SFRP2
SFRP4
SFRP5
SOX17
WIF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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