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Article

Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles.

Aging - 1 Jan 2016

Weilner Sylvia, Keider Verena, Winter Melanie, Harreither Eva, Salzer Benjamin, Weiss Florian, Schraml Elisabeth, Messner Paul, Pietschmann Peter, Hildner Florian, Gabriel Christian, Redl Heinz, Grillari-Voglauer Regina, Grillari Johannes

Abstract excerpt

Aging results in a decline of physiological functions and in reduced repair capacities, in part due to impaired regenerative power of stem cells, influenced by the systemic environment. In particular osteogenic differentiation capacity (ODC) of mesenchymal stem cells (MSCs) has been shown to decrease with age, thereby contributing to reduced bone formation and an increased fracture risk. Searching for systemic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26752347
DOI: 10.18632/aging.100865
PMCID: PMC4761711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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