Article
Small Extracellular Vesicles from Human Bone Marrow Mesenchymal Stromal Cells enhance migration and regulate gene expression of reparative mechanisms in human dermal fibroblasts
2024-07-19
Abstract excerpt
Studies have showed that mesenchymal stromal cells (MSCs) could secrete a variety of bioactive particles, including small extracellular vesicles (sEVs), a type of membrane bound vesicle produced by cells, that might be a key intermediate to the beneficial paracrine effects of MSC therapy. In this study, we harvested the conditioned medium (CM) from both human bone marrow mesenchymal stromal cells (hBM-MSCs) and no...
Topics
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- Cell-Derived Microparticles
- Connective tissue disorders research
- Extracellular vesicles in disease
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Mesenchymal stem cell research
- Pulmonary Hypertension Research and Treatments
- Tissue Engineering and Regenerative Medicine
- Wound Healing and Treatments
Identifiers and source
- Literature Corpus work
- 145f4d7f-e85f-51c4-bd90-cdcea91647b4
- DOI
- 10.1101/2024.07.19.601214
