Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Strong association of the polymorphisms in PBEF1 and knee OA risk: a two-stage population-based study in China.

Scientific reports - 11 Jan 2016

Chu Minjie, Rong Jiesheng, Wang Yidan, Zhu Lin, Xing Baifen, Tao Yuchun, Zhuang Xun, Zhao Yashuang, Jiang Liying

Abstract excerpt

The association of Pre-B cell colony enhancing factor 1 (PBEF1) with obesity, together with its pro-inflammatory properties suggests that PBEF1 might be another crucial mediator that links inflammation with obesity and primary osteoarthritis (OA). We hypothesized that polymorphisms in PBEF1 may modify the risk of developing OA. Thus we systematically screened 4 tagging polymorphisms (rs4730153, rs2058540,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Asian People
Share to Case-Control Studies
Share to China
Share to Cytokines
Share to Genetic Association Studies
Share to Nicotinamide Phosphoribosyltransferase
Share to Osteoarthritis, Knee
Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 26752339
DOI: 10.1038/srep19094
PMCID: PMC4707545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Strong association of the polymorphisms in PBEF1 and knee OA risk: a two-stage population-based study in China.PMID 26752339Read ↗

Integrating polygenic risk scores and constructing a predictive model to assess the risk of knee osteoarthritis in Taiwanese populationSemantic proximity Read ↗

Polymorphism of rs6426749 at 1p36.12 is associated with the risk of osteoarthritis in Taiwanese female population.Semantic proximity Read ↗

Polymorphism rs143384 GDF5 reduces the risk of knee osteoarthritis development in obese individuals and increases the disease risk in non-obese populationSemantic proximity Read ↗

Associations between adipokines gene polymorphisms and knee osteoarthritis: a meta-analysis.Semantic proximity Read ↗

Correlation between growth differentiation factor 5 (rs143383) gene polymorphism and knee osteoarthritis: an updated systematic review and meta-analysis.Semantic proximity Read ↗

A genetic association study between growth differentiation factor 5 (GDF 5) polymorphism and knee osteoarthritis in Thai population.Semantic proximity Read ↗

Association between single nucleotide polymorphisms of sterol regulatory element binding protein-2 gene and risk of knee osteoarthritis in a Chinese Han population.Semantic proximity Read ↗

Association of PPARγ gene polymorphisms with osteoarthritis in a southeast Chinese population.Semantic proximity Read ↗

Genetic polymorphism of PITX1 in susceptibility to knee osteoarthritis in a Chinese Han population: a case-control study.Semantic proximity Read ↗

The Decisive Case-Control Study Elaborates the Null Association between ESR1 XbaI and Osteoarthritis in Asians: A Case-Control Study and Meta-Analysis.Semantic proximity Read ↗

Association of the leptin gene with knee osteoarthritis susceptibility in a Han Chinese population: a case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.