Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism of rs6426749 at 1p36.12 is associated with the risk of osteoarthritis in Taiwanese female population.

Journal of the Chinese Medical Association : JCMA - 1 May 2021

Tsai Dung-Jang, Tai Ming-Cheng, Kao Chung-Cheng, Chen Wei-Teing, Wu Li-Wei, Chiu Chih-Chien, Tu Ming-Yu, Chen Yi-Chou, Wu Chia-Chun, Su Sui-Lung

Abstract excerpt

BACKGROUND: Osteoarthritis (OA) is a multifactorial disease that is associated with several genetic factors. TFAP2A with a motif of C allele at rs6426749 demonstrates a higher binding ability, thereby increasing CDC42 expression, potentially affecting OA occurrence. In this study, we evaluated the role of rs6426749 polymorphisms on knee OA in a female Taiwanese population. METHODS: We performed a case-control...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged
Share to Aged, 80 and over
Share to Alleles
Share to CDC42 gene
Share to Osteoarthritis, Knee
Share to Polymorphism, Single Nucleotide
Share to Risk Factors
Share to Taiwan

Source

Open in PubMed Open full text

Identifiers

PMID: 33742988
DOI: 10.1097/JCMA.0000000000000515
PMCID: PMC12966019

Genes

CDC42
TFAP2A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism of rs6426749 at 1p36.12 is associated with the risk of osteoarthritis in Taiwanese female population.PMID 33742988Read ↗

Association between single nucleotide polymorphisms of sterol regulatory element binding protein-2 gene and risk of knee osteoarthritis in a Chinese Han population.Semantic proximity Read ↗

Integrating polygenic risk scores and constructing a predictive model to assess the risk of knee osteoarthritis in Taiwanese populationSemantic proximity Read ↗

Single nucleotide polymorphisms in the CD40 gene associate with the disease susceptibility and severity in knee osteoarthritis in the Chinese Han population: a case-control study.Semantic proximity Read ↗

Genetics of osteoarthritis.Semantic proximity Read ↗

The Genetic Epidemiological Landscape of Hip and Knee Osteoarthritis: Where Are We Now and Where Are We Going?Semantic proximity Read ↗

The Genetics and Functional Genomics of Osteoarthritis.Semantic proximity Read ↗

Evaluation of Relationship Between Common Variants in FGF18 Gene and Knee Osteoarthritis Susceptibility.Semantic proximity Read ↗

Genetics of osteoarthritis.Semantic proximity Read ↗

The rs4238326 polymorphism in ALDH1A2 gene potentially associated with non-post traumatic knee osteoarthritis susceptibility: a two-stage population-based study.Semantic proximity Read ↗

Single Nucleotide Polymorphisms and Osteoarthritis: An Overview and a Meta-Analysis.Semantic proximity Read ↗

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis.Semantic proximity Read ↗

The Genetics of Osteoarthritis: A ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.