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Article

Genetic polymorphism of PITX1 in susceptibility to knee osteoarthritis in a Chinese Han population: a case-control study.

Rheumatology international - 1 May 2011

Fan Jianbo, Shi Dongquan, Dai Jin, Zhu Lunqing, Qin Jianghui, Shao Zhenxing, Qiu Xusheng, Xu Zhihong, Chen Dongyang, Jiang Qing

Abstract excerpt

Osteoarthritis (OA) is the most common form of arthritis and the precise etiology of this disease remains unclear. Genetic factors play a considerable role in pathogenesis of OA. Several OA-susceptibility genes have been identified. Recently, a new emerging role of pitx1 transcription factor in OA pathogenesis has been reported. Paired-like homeodomain transcription factor 1 (PITX1) has been implicated in hind...

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Identifiers

PMID: 20054692
DOI: 10.1007/s00296-009-1341-5

Genes

PITX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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