Correlation between growth differentiation factor 5 (rs143383) gene polymorphism and knee osteoarthritis: an updated systematic review and meta-analysis.

doi:10.1186/s13018-021-02269-w

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Article

Correlation between growth differentiation factor 5 (rs143383) gene polymorphism and knee osteoarthritis: an updated systematic review and meta-analysis.

Journal of orthopaedic surgery and research - 19 Feb 2021

Jia Bin, Jiang Yaping, Xu Yingxing, Wang Yingzhen, Li Tao

Abstract excerpt

BACKGROUND: A great deal of evidence has supported that growth differentiation factor 5 (GDF5) is associated with the occurrence of knee osteoarthritis (KOA), while their results are not consistent. In the present study, we aimed to explore the association between GDF5 gene polymorphism and KOA for a more credible conclusion. METHODS: Comprehensive literature searches were carried out in English databases,...

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PMID: 33608035
DOI: 10.1186/s13018-021-02269-w
PMCID: PMC7893760

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