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Article

Sustained viral response and treatment-induced cytopenia correlate with SLCs and KLF12 genotypes in interferon/ribavirin-treated Chinese chronic hepatitis C patients.

Journal of gastroenterology and hepatology - 1 Aug 2016

Mei Ruqi, Chi Xiumei, Wu Ruihong, Xu Hongqin, Wang Xiaomei, Gao Xiuzhu, Sun Haibo, Lv Juan, Yu Ge, Kong Fei, Jiang Jing, Sun Bing, Zhong Jin, Pan Yu, Niu Junqi

Abstract excerpt

BACKGROUND AND AIM: Genetic variations in solute carrier (SLC) genes are associated with liver diseases, and Kruppel-like factor 12 (KLF12) affects the b chain of hemoglobin. We investigated possible correlations of SLC and KLF12 polymorphisms with viral clearance (spontaneous and treatment-induced) and adverse effects in Chinese chronic hepatitis C (CHC) patients. METHODS: We genotyped the single nucleotide...

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PMID: 26750805
DOI: 10.1111/jgh.13290

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KLF12

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