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Article

Association of genetic polymorphisms with interferon-induced haematologic adverse effects in chronic hepatitis C patients.

Journal of viral hepatitis - 1 Jun 2009

Wada M, Marusawa H, Yamada R, Nasu A, Osaki Y, Kudo M, Nabeshima M, Fukuda Y, Chiba T, Matsuda F

Abstract excerpt

Interferon (IFN)-based combination therapy with ribavirin has become the gold standard for the treatment of chronic hepatitis C virus infection. Haematologic toxicities, such as neutropenia, thrombocytopenia, and anaemia, however, frequently cause poor treatment tolerance, resulting in poor therapeutic efficacy. The aim of this study was to identify host genetic polymorphisms associated with the efficacy or...

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Share to Hepatitis C, Chronic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Interferon alpha-beta

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Source

Identifiers

PMID: 19200137
DOI: 10.1111/j.1365-2893.2009.01095.x

Genes

IFNAR1
STAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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