Article
Association between the surfactant protein D (SFTPD) gene and subclinical carotid artery atherosclerosis.
Atherosclerosis - 1 Mar 2016
Sorensen Grith L, Bladbjerg Else Marie, Steffensen Rudi, Tan Qihua, Madsen Jens, Drivsholm Thomas, Holmskov Uffe
Abstract excerpt
OBJECTIVE: Surfactant protein D (SP-D) is a defense collectin with inflammation-modulating properties. SP-D deficiency inhibits atherosclerosis in vivo, and the circulatory SP-D levels have been previously associated with cardiovascular disease mortality. We hypothesized that plasma SP-D (pSP-D) and SP-D gene (SFTPD) single nucleotide polymorphisms (SNPs) are risk factors for atherosclerosis. METHODS: We...
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