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Article

Involvement of surfactant protein D in emphysema revealed by genetic association study.

European journal of human genetics : EJHG - 1 Feb 2012

Ishii Takeo, Hagiwara Koichi, Kamio Koichiro, Ikeda Shinobu, Arai Tomio, Mieno Makiko Naka, Kumasaka Toshio, Muramatsu Masaaki, Sawabe Motoji, Gemma Akihiko, Kida Kozui

Abstract excerpt

Surfactant protein D (SFTPD) induces emphysema in knockout mice, but the association of SFTPD with chronic obstructive pulmonary disease (COPD) and emphysema in humans is unclear. Therefore, we aimed to determine the association between genetic variations in SFTPD and susceptibility to COPD and emphysema.Two populations were studied: population A comprised 270 smokers, including 188 COPD and 82 at-risk subjects,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21934714
DOI: 10.1038/ejhg.2011.183
PMCID: PMC3260918

Genes

SFTPD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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