Article
Common genetic variants of surfactant protein-D (SP-D) are associated with type 2 diabetes.
PloS one - 1 Jan 2013
Pueyo Neus, Ortega Francisco J, Mercader Josep M, Moreno-Navarrete José M, Sabater Monica, Bonàs Sílvia, Botas Patricia, Delgado Elías, Ricart Wifredo, Martinez-Larrad María T, Serrano-Ríos Manuel, Torrents David, Fernández-Real José M
Abstract excerpt
CONTEXT: Surfactant protein-D (SP-D) is a primordial component of the innate immune system intrinsically linked to metabolic pathways. We aimed to study the association of single nucleotide polymorphisms (SNPs) affecting SP-D with insulin resistance and type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS: We evaluated a common genetic variant located in the SP-D coding region (rs721917, Met(31)Thr) in a sample of...
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