Article
BDNF Serum Levels with Respect to Multidimensional Assessment in Amyotrophic Lateral Sclerosis.
Neuro-degenerative diseases - 1 Jan 2016
Tremolizzo Lucio, Pellegrini Andrea, Conti Elisa, Arosio Alessandro, Gerardi Francesca, Lunetta Christian, Magni Paolo, Appollonio Ildebrando, Ferrarese Carlo
Abstract excerpt
BACKGROUND: The clinical presentation of amyotrophic lateral sclerosis (ALS) is characterized by high heterogeneity, the greatest part of which still remains unexplained. OBJECTIVE: To assess serum levels of brain-derived neurotrophic factor (BDNF) in ALS patients, implementing a multidimensional characterization focused on four a priori chosen elements of phenotypic variability: ALS bulbar/spinal subtype,...
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