Article

Multifactorial Therapeutic Strategies Targeting Advanced Glycation End-Products, Oxidative Stress, and Metabolic Dysfunction in Alzheimer's Disease

2024-12-28

Abstract excerpt

This study explores the complex pathogenesis of Alzheimer’s disease (AD), emphasizing the critical roles of advanced glycation end-products (AGEs), oxidative stress, and metabolic dysfunctions. The AGE-RAGE pathway is highlighted for its contribution to neurodegeneration, amyloid-beta (Aβ) accumulation, and tau protein pathology, proposing it as a possible treatment target. Natural compounds, such as antioxidants...

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Literature Corpus work: 2c6017ca-8680-54e7-b006-bfa4d4672464
DOI: 10.22541/au.173542385.56166052/v1

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