Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ADAMTS12, a new candidate gene for pediatric stroke.

PloS one - 1 Jan 2020

Witten Anika, Rühle Frank, de Witt Marlous, Barysenka Andrei, Stach Michael, Junker Ralf, Nowak-Göttl Ulrike, Stoll Monika

Abstract excerpt

We recently reported a family-based genome wide association study (GWAS) for pediatric stroke pointing our attention to two significantly associated genes of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) gene family ADAMTS2 (rs469568, p = 8x10-6) and ADAMTS12 (rs1364044, p = 2.9x10-6). To further investigate these candidate genes, we applied a targeted resequencing approach on 48...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ADAMTS Proteins

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Haplotypes

Share to Pediatrics

Share to Polymorphism, Single Nucleotide

Share to Stroke

Source

Open in PubMed Open full text

Identifiers

PMID: 32817637
DOI: 10.1371/journal.pone.0237928
PMCID: PMC7446847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ADAMTS12, a new candidate gene for pediatric stroke.PMID 32817637Read ↗

Rare Variants in the ADAMTS13 Von Willebrand Factor-Binding Domain Contribute to Pediatric Stroke.Semantic proximity Read ↗

A genome-wide association study identifies a gene network of ADAMTS genes in the predisposition to pediatric stroke.Semantic proximity Read ↗

ADAMTS genes and the risk of cerebral aneurysm.Semantic proximity Read ↗

The Genetic Basis of Strokes in Pediatric Populations and Insight into New Therapeutic Options.Semantic proximity Read ↗

Genome-wide association study of ischemic stroke risk in Sickle Cell confirms <i>ADAMTS2, CDK18</i>, uncovers 12 novel lociSemantic proximity Read ↗

Advances in understanding stroke risk in children--a geneticist's view.Semantic proximity Read ↗

ADAMTS proteins in human disorders.Semantic proximity Read ↗

Genomic Landscape and Mutational Spectrum of ADAMTS Family Genes in Mendelian Disorders Based on Gene Evidence Review for Variant Interpretation.Semantic proximity Read ↗

The role of genetic risk factors in arterial ischemic stroke in pediatric and adult patients: a critical review.Semantic proximity Read ↗

Inherited risk factors for thrombotic diseases in children: the genome-wide perspective.Semantic proximity Read ↗

Association of SERPINE1 rs1799889 polymorphism with arterial ischemic stroke in children: a systematic review and meta-analysis.Semantic proximity Read ↗

Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.