Article
The versican gene and the risk of intracranial aneurysms.
Stroke - 1 Sept 2006
Ruigrok Ynte M, Rinkel Gabriël J E, Wijmenga Cisca
Abstract excerpt
BACKGROUND AND PURPOSE: The proteoglycan versican is an excellent candidate gene for intracranial aneurysms (IAs) because it plays an important role in extracellular matrix assembly and is localized in a previously implicated locus for IAs on chromosome 5q. METHODS: We analyzed all the common variations using 16-tag single nucleotide polymorphisms (SNPs) and haplotypes in the versican gene using a 2-stage...
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