Article
Single Nucleotide Polymorphisms in STAT3 and STAT4 and Risk of Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Chanthra Nawin, Payungporn Sunchai, Chuaypen Natthaya, Piratanantatavorn Kesmanee, Pinjaroen Nutcha, Poovorawan Yong, Tangkijvanich Pisit
Abstract excerpt
Hepatitis B virus (HBV) infection is the leading cause of hepatocellular carcinoma (HCC) development. Recent studies demonstrated that single nucleotide polymorphisms (SNPs) rs2293152 in signal transducer and activator of transcription 3 (STAT3) and rs7574865 in signal transducer and activator of transcription 4 (STAT4) are associated with chronic hepatitis B (CHB)-related HCC in the Chinese population. We...
Topics
- Biomarkers, Tumor
- Carcinoma, Hepatocellular
- Case-Control Studies
- Female
- Follow-Up Studies