Article
Association of VARS2-SFTA2 polymorphisms with the risk of chronic hepatitis B in a Korean population.
Liver international : official journal of the International Association for the Study of the Liver - 1 Aug 2015
Cheong Hyun Sub, Lee Jeong-Hoon, Yu Su Jong, Yoon Jung-Hwan, Lee Hyo-Suk, Cheong Jae Youn, Cho Sung Won, Park Neung Hwa, Park Byung Lae, Namgoong Suhg, Kim Lyoung Hyo, Shin Hyoung Doo, Kim Yoon-Jun
Abstract excerpt
BACKGROUND & AIMS: Hepatitis B virus (HBV) infection is the most serious risk factor for chronic hepatitis B (CHB), cirrhosis, and hepatocellular carcinoma. Recently, several genome-wide association studies (GWASs) identified important variants associated with the risk of CHB in Asian populations. Specifically, our previous GWAS identified the VARS2-SFTA2 gene region as one of the genetic risk loci for CHB....
Topics
- Adult
- Asian People
- Case-Control Studies
- Confidence Intervals
- Female
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Genotype
- HLA Antigens