Genetic variations in STAT4,C2,HLA-DRB1 and HLA-DQ associated with risk of hepatitis B virus-related liver cirrhosis.

doi:10.1038/srep16278

Article

Genetic variations in STAT4,C2,HLA-DRB1 and HLA-DQ associated with risk of hepatitis B virus-related liver cirrhosis.

Scientific reports - 5 Nov 2015

Jiang De-Ke, Ma Xiao-Pin, Wu Xiaopan, Peng Lijun, Yin Jianhua, Dan Yunjie, Huang Hui-Xing, Ding Dong-Lin, Zhang Lu-Yao, Shi Zhuqing, Zhang Pengyin, Yu Hongjie, Sun Jielin, Lilly Zheng S, Deng Guohong, Xu Jianfeng, Liu Ying, Guo Jinsheng, Cao Guangwen, Yu Long

Abstract excerpt

Recent genome-wide associated studies (GWASs) have revealed several common loci associated with the risk of hepatitis B virus (HBV)- or hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). We selected 15 single nucleotide polymorphisms (SNPs) identified through GWASs on HBV- or HCV-rel...

Topics

Carcinoma, Hepatocellular
Case-Control Studies
China
Female
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
HLA-DQ Antigens
HLA-DRB1 Chains
Hepatitis B virus

Hepatitis B, Chronic

Humans

Liver Cirrhosis

Liver Neoplasms

Male

Middle Aged

Polymorphism, Single Nucleotide

Risk

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