Article
Genetic variations in STAT4,C2,HLA-DRB1 and HLA-DQ associated with risk of hepatitis B virus-related liver cirrhosis.
Scientific reports - 5 Nov 2015
Jiang De-Ke, Ma Xiao-Pin, Wu Xiaopan, Peng Lijun, Yin Jianhua, Dan Yunjie, Huang Hui-Xing, Ding Dong-Lin, Zhang Lu-Yao, Shi Zhuqing, Zhang Pengyin, Yu Hongjie, Sun Jielin, Lilly Zheng S, Deng Guohong, Xu Jianfeng, Liu Ying, Guo Jinsheng, Cao Guangwen, Yu Long
Abstract excerpt
Recent genome-wide associated studies (GWASs) have revealed several common loci associated with the risk of hepatitis B virus (HBV)- or hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). We selected 15 single nucleotide polymorphisms (SNPs) identified through GWASs on HBV- or HCV-related HCC, and genotyped them in two independent Chinese cohorts of chronic HBV carriers, including 712 LC cases and...
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