Article
Interaction of signal transducer and activator of transcription 3 polymorphisms with hepatitis B virus mutations in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) - 1 Jun 2013
Xie Jiaxin, Zhang Yuwei, Zhang Qi, Han Yifang, Yin Jianhua, Pu Rui, Shen Qiuxia, Lu Wei, Du Yan, Zhao Jun, Han Xue, Zhang Hongwei, Cao Guangwen
Abstract excerpt
UNLABELLED: Hepatitis B virus (HBV) mutations and signal transducer and activator of transcription 3 (STAT3) activation are closely associated with hepatocellular carcinoma (HCC). However, single nucleotide polymorphisms (SNPs) of STAT3 have not been implicated in HCC susceptibility. This study was designed to evaluate the effect of STAT3 SNPs and their interactions with HBV mutations on HCC risk. A total of...
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