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Article

STAT4 gene polymorphism and risk of chronic hepatitis B-induced hepatocellular carcinoma.

Cell biochemistry and biophysics - 1 Jan 2015

Zhao Xiangqian, Jiang Kai, Liang Bin, Huang Xiaoqiang

Abstract excerpt

STAT4 is a latent cytosolic factor that encodes a transcription factor transmitting signals stimulated by cytokines. Previous studies with different study designs in diverse ethnic populations have assessed the influence of STAT4 rs7574865 polymorphism on HBV-induced HCC risk. The aim of the current study was to investigate the effects in a larger sample. The individual reports published up to Dec. 30, 2013 were...

Topics

Carcinoma, Hepatocellular
Genetic Predisposition to Disease
Hepatitis B, Chronic
Humans
Liver Neoplasms
Polymorphism, Single Nucleotide
STAT4 Transcription Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25178516
DOI: 10.1007/s12013-014-0205-0

Genes

STAT4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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STAT4 gene polymorphism and risk of chronic hepatitis B-induced hepatocellular carcinoma.PMID 25178516Read ↗

A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B.Semantic proximity Read ↗

The effects of the interactions of STAT4 rs7574865 with HBV mutations on the risk of hepatocellular carcinoma.Semantic proximity Read ↗

Single Nucleotide Polymorphisms in STAT3 and STAT4 and Risk of Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B.Semantic proximity Read ↗

Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma.Semantic proximity Read ↗

A trivial role of STAT4 variant in chronic hepatitis B induced hepatocellular carcinoma.Semantic proximity Read ↗

STAT4 genetic polymorphisms association with spontaneous clearance of hepatitis B virus infection.Semantic proximity Read ↗

Evaluation of STAT3 rs1053004 single nucleotide polymorphism in patients with chronic hepatitis B and hepatocellular carcinoma.Semantic proximity Read ↗

Genetic variants in STAT4 and their interactions with environmental factors for the incidence of hepatocellular carcinoma.Semantic proximity Read ↗

Genetic variations in STAT4,C2,HLA-DRB1 and HLA-DQ associated with risk of hepatitis B virus-related liver cirrhosis.Semantic proximity Read ↗

Association of Single Nucleotide Polymorphism rs1053004 in Signal Transducer and Activator of Transcription 3 (STAT3) with Susceptibility to Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B.Semantic proximity Read ↗

A new discovery of STAT4 single nucleotide polymorphisms associated with hepatocellular carcinoma risk in Chinese Han population: a case-control study.Semantic proximity Read ↗

Association of polymorphism rs1053005 in STAT3 with chronic hepatitis B virus infection in Han Chinese population.Semantic proximity Read ↗

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