Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Replication of genome wide association studies on hepatocellular carcinoma susceptibility loci of STAT4 and HLA-DQ in a Korean population.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2015

Kim Lyoung Hyo, Cheong Hyun Sub, Namgoong Suhg, Kim Ji On, Kim Jeong-Hyun, Park Byung Lae, Cho Sung Won, Park Neung Hwa, Cheong Jae Youn, Koh InSong, Shin Hyoung Doo, Kim Yoon-Jun

Abstract excerpt

A recent genome-wide association study (GWAS) for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) identified two loci (rs7574865 in STAT4 and rs9275319 in HLA-DQ) in a Chinese population. We attempted to replicate the associations between the two SNP loci and the risk of HCC in a Korean population. The rs7574865 in STAT4 and rs9275319 in HLA-DQ were genotyped in a total of 3838 Korean subjects...

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Alleles
Asian People
Carcinoma, Hepatocellular
Case-Control Studies
Female
Gene Expression
Gene Frequency
Genetic Loci
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
HLA-DQ Antigens
Humans
Liver Neoplasms
Male
Polymorphism, Single Nucleotide
Republic of Korea
Risk Factors

Source

Identifiers

PMID: 25913043
DOI: 10.1016/j.meegid.2015.04.013

Genes

STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-25913043-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replication of genome wide association studies on hepatocellular carcinoma susceptibility loci of STAT4 and HLA-DQ in a Korean population.PMID 25913043Read ↗

Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma.Semantic proximity Read ↗

Genetic variations in STAT4,C2,HLA-DRB1 and HLA-DQ associated with risk of hepatitis B virus-related liver cirrhosis.Semantic proximity Read ↗

Replication of genome wide association studies on hepatocellular carcinoma susceptibility loci in a Chinese population.Semantic proximity Read ↗

Single Nucleotide Polymorphisms in STAT3 and STAT4 and Risk of Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B.Semantic proximity Read ↗

The effects of the interactions of STAT4 rs7574865 with HBV mutations on the risk of hepatocellular carcinoma.Semantic proximity Read ↗

A new discovery of STAT4 single nucleotide polymorphisms associated with hepatocellular carcinoma risk in Chinese Han population: a case-control study.Semantic proximity Read ↗

Genome-wide association study: new genetic insights into HBV/HCV-related hepatocellular carcinoma genomes.Semantic proximity Read ↗

Association of Single Nucleotide Polymorphism rs1053004 in Signal Transducer and Activator of Transcription 3 (STAT3) with Susceptibility to Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B.Semantic proximity Read ↗

Genetic variants in STAT4 and their interactions with environmental factors for the incidence of hepatocellular carcinoma.Semantic proximity Read ↗

A trivial role of STAT4 variant in chronic hepatitis B induced hepatocellular carcinoma.Semantic proximity Read ↗

Genetic polymorphism of HLA-DQ confers susceptibility to hepatitis B virus-related hepatocellular carcinoma: a case-control study in Han population in China.Semantic proximity Read ↗

Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.