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Article

BDNF Val66Met genotype and neuroticism predict life stress: A longitudinal study from childhood to adulthood.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Mar 2016

Lehto Kelli, Mäestu Jarek, Kiive Evelyn, Veidebaum Toomas, Harro Jaanus

Abstract excerpt

The brain-derived neurotrophic factor gene (BDNF) Val66Met polymorphism and life stress have been associated with negative emotionality (e.g., neuroticism), but relevant evidence is far from unequivocal. Possible confounding factors include the type and timing of stressful events measured, such as childhood adversity vs. recent stressful events, and variable gene × environment interactions. The aim of this study...

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Source

Identifiers

PMID: 26738427
DOI: 10.1016/j.euroneuro.2015.12.029

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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BDNF Val66Met genotype and neuroticism predict life stress: A longitudinal study from childhood to adulthood.PMID 26738427Read ↗

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