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Article

Challenges posed to pathologists in the detection of KRAS mutations in colorectal cancers.

Archives of pathology & laboratory medicine - 1 Feb 2015

Dudley Jonathan, Tseng Li-Hui, Rooper Lisa, Harris Marco, Haley Lisa, Chen Guoli, Gocke Christopher D, Eshleman James R, Lin Ming-Tseh

Abstract excerpt

CONTEXT: Detection of KRAS mutation is mandatory to predict response to anti-epidermal growth factor receptor monoclonal antibodies in patients with metastatic colorectal cancers. OBJECTIVE: To demonstrate challenges posed to pathologists in the clinical detection of KRAS mutations in colorectal cancers. DESIGN: In this retrospective analysis for quality assessment of the pyrosequencing assay, we survey the...

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PMID: 25611103
DOI: 10.5858/arpa.2013-0649-OA

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KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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