Article
Aberrant brain network topology in youth with a familial risk for bipolar disorder: a task-based fMRI connectome study.
Journal of child psychology and psychiatry, and allied disciplines - 1 Aug 2024
Pan Nanfang, Qin Kun, Patino Luis R, Tallman Maxwell J, Lei Du, Lu Lu, Li Wenbin, Blom Thomas J, Bruns Kaitlyn M, Welge Jeffrey A, Strawn Jeffrey R, Gong Qiyong, Sweeney John A, Singh Manpreet K, DelBello Melissa P
Abstract excerpt
BACKGROUND: Youth with a family history of bipolar disorder (BD) may be at increased risk for mood disorders and for developing side effects after antidepressant exposure. The neurobiological basis of these risks remains poorly understood. We aimed to identify biomarkers underlying risk by characterizing abnormalities in the brain connectome of symptomatic youth at familial risk for BD. METHODS: Depressed and/or...
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