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Article

Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis.

Genes & development - 1 Jan 2016

Shimojo Hiromi, Isomura Akihiro, Ohtsuka Toshiyuki, Kori Hiroshi, Miyachi Hitoshi, Kageyama Ryoichiro

Abstract excerpt

Notch signaling regulates tissue morphogenesis through cell-cell interactions. The Notch effectors Hes1 and Hes7 are expressed in an oscillatory manner and regulate developmental processes such as neurogenesis and somitogenesis, respectively. Expression of the mRNA for the mouse Notch ligand Delta-like1 (Dll1) is also oscillatory. However, the dynamics of Dll1 protein expression are controversial, and their...

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Identifiers

PMID: 26728556
DOI: 10.1101/gad.270785.115
PMCID: PMC4701973

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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