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Article

Probing interactions of Vpu from HIV-1 with amiloride-based compounds.

Biochimica et biophysica acta - 1 Apr 2016

Rosenberg Matthew R, Weaver Llara M, Casarotto Marco G

Abstract excerpt

Viral ion channels or viroporins are short membrane proteins that participate in wide-ranging functions including virus replication and entry, assembly, and virus release. One such viroporin is the 81 amino acid residue Vpu protein derived from HIV-1. This protein consists of one transmembrane (TM) and two cytoplasmic helical domains, the former of which oligomerises to form cation-selective ion channels. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26724207
DOI: 10.1016/j.bbamem.2015.12.028

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SPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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