Article
Phenotype of NK Cells Determined on the Basis of Selected Immunological Parameters in Children Treated due to Acute Lymphoblastic Leukemia.
Medicine - 1 Dec 2015
Koltan Sylwia, Debski Robert, Koltan Andrzej, Grzesk Elzbieta, Tejza Barbara, Eljaszewicz Andrzej, Gackowska Lidia, Kubicka Malgorzata, Kolodziej Beata, Kurylo-Rafinska Beata, Kubiszewska Izabela, Wiese Malgorzata, Januszewska Milena, Michalkiewicz Jacek, Wysocki Mariusz, Styczynski Jan, Grzesk Grzegorz
Abstract excerpt
Acute lymphoblastic leukemia (ALL) is the most frequent pediatric malignancy. The chemotherapy for ALL is associated with a profound secondary immune deficiency.We evaluated the number and phenotype of natural killer (NK) cells at diagnosis, after the intensive chemotherapy and following the completion of the entire treatment for patients with ALL. The fraction, absolute number, and percentage of NK cells...
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