Article
Abnormalities of quantities and functions of natural killer cells in severe aplastic anemia.
Immunological investigations - 1 Jan 2014
Liu Chunyan, Li Zhishang, Sheng Weiwei, Fu Rong, Li Lijuan, Zhang Tian, Wu Yuhong, Xing Limin, Song Jia, Wang Huaquan, Shao Zonghong
Abstract excerpt
Severe aplastic anemia (SAA) is a rare disease characterized by severe pancytopenia and bone marrow failure. Natural killer (NK) cells are large granular lymphocytes derived from hematopoietic stem cells (HSCs) or common lymphoid progenitors (CLP). They play a key role in n the innate immunity and adaptive immune. In this study, the quantitative and functional changes of natural killer (NK) cell subsets in...
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