Article
NKG2A discriminates natural killer cells with a suppressed phenotype in pediatric acute leukemia.
Journal of leukocyte biology - 19 Jan 2024
Ulvmoen Aina, Greiff Victor, Bechensteen Anne G, Inngjerdingen Marit
Abstract excerpt
Natural killer (NK) cells are important for early tumor immune surveillance. In patients with hematological cancers, NK cells are generally functional deficient and display dysregulations in their receptor repertoires. Acute leukemia is the most common cancer in children, and we here performed a comparative phenotypic profiling of NK cells from B-cell precursor acute lymphoblastic leukemia (BCP-ALL) patients to...
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