Article
Identification of natural killer cell receptor phenotypes associated with leukemia.
Leukemia - 1 Dec 2004
Verheyden S, Bernier M, Demanet C
Abstract excerpt
Natural killer (NK) cells play a key role in defense against tumor cells that have the capacity to downregulate human leukocyte antigen (HLA) class I expression. It has been reported that leukemic cells can have downregulated expression of HLA class I molecules. The polymorphic nature of NK cell receptor (NKR) genes generates diverse repertoires in the human population, which display specificity in the innate...
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