High-Risk Leukemia: Past, Present, and Future Role of NK Cells

doi:10.1155/2018/1586905

Article

High-Risk Leukemia: Past, Present, and Future Role of NK Cells

1 Jan 2018

Abstract excerpt

Natural killer (NK) cells are a population of cytotoxic innate lymphocytes that evolved prior to their adaptive counterparts and constitute one of the first lines of defense against infected/mutated cells. Several studies have shown that in patients with acute leukemia given haploidentical hematopoietic stem cell transplantation, donor-derived NK cells play a key role in the eradication of cancer cells. The...

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