Article
A20 Mutation Is Not a Prognostic Marker for Activated B-Cell-Like Diffuse Large B-Cell Lymphoma.
PloS one - 1 Jan 2015
Cen Hong, Tan Xiaohong, Guo Baoping
Abstract excerpt
BACKGROUND: Constitutive activation of nuclear factor κB (NF-κB) is a hallmark of activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL). Mutations in the A20 gene activate NF-κB, but the prognostic value of A20 mutations in ABC-DLBLC is unclear. PURPOSE: To investigate the prognostic value of A20 mutation in ABC-DLBCL patients. METHODS: The somatic mutation of A20 was investigated in 68 de novo...
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