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Article

Immunohistochemical Detection of NRASQ61R Mutation in Diverse Tumor Types.

American journal of clinical pathology - 1 Jan 2016

Dias-Santagata Dora, Su Yuhua, Hoang Mai P

Abstract excerpt

OBJECTIVES: Testing for NRAS mutation at codon Q61 is of therapeutic, prognostic, and diagnostic importance for metastatic melanoma, thyroid carcinoma, and colorectal carcinoma. Immunohistochemistry for NRASQ61R, the most common NRAS mutation, offers several practical advantages over current molecular diagnostic techniques. METHODS: We investigated the sensitivity and specificity of NRASQ61R in a series of 149...

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Identifiers

PMID: 26712868
DOI: 10.1093/ajcp/aqv015

Genes

NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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