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Article

Clinical outcome and pathological features associated with NRAS mutation in cutaneous melanoma.

Pigment cell & melanoma research - 1 Aug 2011

Devitt Bianca, Liu Wendy, Salemi Renato, Wolfe Rory, Kelly John, Tzen Chin-Yuan, Dobrovic Alexander, McArthur Grant

Abstract excerpt

The effect of NRAS mutations on the pathological features and clinical outcomes in patients with cutaneous melanoma was compared with that of tumors containing BRAF(V600E) mutations and tumors wild type for both (WT). Clinical outcome data were obtained from a prospective cohort of 249 patients. Mutations involving NRAS and BRAF(V600E) were detected by PCR and were sequence verified. Cox proportional hazards...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21615881
DOI: 10.1111/j.1755-148X.2011.00873.x

Genes

NRAS
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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