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Article

NRASQ61R immunohistochemistry detects both NRASQ61R and KRASQ61R mutations in colorectal cancer.

Pathology - 1 Jun 2017

Jhuang Jie-Yang, Yuan Chang-Tsu, Lin Yu-Lin, Cheng Mei-Ling, Liau Jau-Yu, Tsai Jia-Huei

Abstract excerpt

The NRASQ61R monoclonal antibody (clone sp174) is a mutation-specific antibody that is increasingly being used to detect the NRASQ61R mutation in melanomas. This antibody has been reported to be highly correlated with the NRASQ61R mutation status in melanomas and follicular neoplasms of the thyroid gland. However, its utility in colorectal carcinoma (CRC) has remained largely unknown. In this study, we assessed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28433252
DOI: 10.1016/j.pathol.2017.01.008

Genes

BRAF
KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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