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Article

NRAS Q61R immunohistochemical staining in thyroid pathology: sensitivity, specificity and utility.

Histopathology - 1 Oct 2021

Saliba Maelle, Katabi Nora, Dogan Snjezana, Xu Bin, Ghossein Ronald A

Abstract excerpt

AIMS: The diagnosis of thyroid neoplasms relies upon the demonstration of histological parameters that can be focal and prone to subjective interpretation. We evaluated the utility of NRAS Q61R immunohistochemistry (IHC) in the diagnosis of thyroid lesions after determining its specificity and sensitivity as a surrogate marker for RAS Q61R mutation. METHOD AND RESULTS: NRAS Q61R IHC was performed on 282 primary...

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Identifiers

PMID: 33960437
DOI: 10.1111/his.14396
PMCID: PMC8458224

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