Article
The association between two polymorphisms in pre-miRNAs and breast cancer risk: a meta-analysis.
Breast cancer research and treatment - 1 Jan 2011
Gao Lin-Bo, Bai Peng, Pan Xin-Min, Jia Jing, Li Li-Juan, Liang Wei-Bo, Tang Ming, Zhang Lu-Shun, Wei Yong-Gang, Zhang Lin
Abstract excerpt
Emerging evidence has shown that miRNAs participate in human carcinogenesis as tumor suppressors or oncogenes. Single nucleotide polymorphism (SNP) which located in the pre-miRNA may affect the processing and then influence the expression of mature miRNA. Previous studies yielded conflicting results as to the association of two common polymorphisms in pre-miRNAs (i.e. hsa-miR-146 rs2910164 and hsa-miR-196a2...
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