Article
Regionally Smoothed Meta-Analysis Methods for GWAS Datasets.
Genetic epidemiology - 1 Feb 2016
Begum Ferdouse, Sharker Monir H, Sherman Stephanie L, Tseng George C, Feingold Eleanor
Abstract excerpt
Genome-wide association studies are proven tools for finding disease genes, but it is often necessary to combine many cohorts into a meta-analysis to detect statistically significant genetic effects. Often the component studies are performed by different investigators on different populations, using different chips with minimal SNPs overlap. In some cases, raw data are not available for imputation so that only...
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