Article
Dealing with heterogeneity between cohorts in genomewide SNP association studies.
Statistical applications in genetics and molecular biology - 1 Jan 2010
Lebrec Jeremie J, Stijnen Theo, van Houwelingen Hans C
Abstract excerpt
In Genomewide association (GWA) studies investigating thousands of SNPs, large sample sizes are needed to obtain a reasonable power after correction for multiple testing. To obtain the necessary sample sizes, data from different populations/cohorts are combined. The problem of pooling evidence ac...
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