Article
Anthrax Susceptibility: Human Genetic Polymorphisms Modulating ANTXR2 Expression.
Toxins - 22 Dec 2015
Zhang Zhang, Zhang Yan, Shi Minglei, Ye Bingyu, Shen Wenlong, Li Ping, Xing Lingyue, Zhang Xiaopeng, Hou Lihua, Xu Junjie, Zhao Zhihu, Chen Wei
Abstract excerpt
Anthrax toxin causes anthrax pathogenesis and expression levels of ANTXR2 (anthrax toxin receptor 2) are strongly correlated with anthrax toxin susceptibility. Previous studies found that ANTXR2 transcript abundance varies considerably in individuals of different ethnic/geographical groups, but no eQTLs (expression quantitative trait loci) have been identified. By using 3C (chromatin conformation capture),...
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