Article
ANTXR2 is a potential causative gene in the genome-wide association study of the blood pressure locus 4q21.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Sept 2014
Park So Yon, Lee Hyeon-Ju, Ji Su-Min, Kim Marina E, Jigden Baigalmaa, Lim Ji Eun, Oh Bermseok
Abstract excerpt
Hypertension is the most prevalent cardiovascular disease worldwide, but its genetic basis is poorly understood. Recently, genome-wide association studies identified 33 genetic loci that are associated with blood pressure. However, it has been difficult to determine whether these loci are causative owing to the lack of functional analyses. Of these 33 genome-wide association studies (GWAS) loci, the 4q21 locus,...
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