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Article

Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene (ANTXR2).

Annals of the rheumatic diseases - 1 Nov 2014

Karaderi T, Keidel S M, Pointon J J, Appleton L H, Brown M A, Evans D M, Wordsworth B P

Abstract excerpt

OBJECTIVES: ANTXR2 variants have been associated with ankylosing spondylitis (AS) in two previous genome-wide association studies (GWAS) (p∼9×10(-8)). However, a genome-wide significant association (p<5×10(-8)) was not observed. We conducted a more comprehensive analysis of ANTXR2 in an independent UK sample to confirm and refine this association. METHODS: A replication study was carried out with 2978 cases and...

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Identifiers

PMID: 25169729
DOI: 10.1136/annrheumdis-2014-205643
PMCID: PMC4215346

Genes

ANTXR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ankylosing spondylitis is associated with the anthrax toxin receptor 2 gene (ANTXR2).PMID 25169729Read ↗

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