P-Glycoprotein Polymorphism C3435T Is Associated with Dose-Adjusted Clopidogrel and 2-Oxo-Clopidogrel Concentration.

doi:10.1159/000442712

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Article

P-Glycoprotein Polymorphism C3435T Is Associated with Dose-Adjusted Clopidogrel and 2-Oxo-Clopidogrel Concentration.

Pharmacology - 1 Jan 2016

Stokanovic Dragana, Nikolic Valentina N, Konstantinovic Sandra S, Zvezdanovic Jelena B, Lilic Jelena, Apostolovic Svetlana R, Pavlovic Milan, Zivkovic Vladimir S, Jevtovic-Stoimenov Tatjana, Jankovic Slobodan M

Abstract excerpt

BACKGROUND/AIMS: One of the most common polymorphisms of ABCB1 gene, a synonymous mutation C3435T (rs1045642), is associated with increased in vivo activity. The main goal of this study was to determine the association of C3435T polymorphism with clopidogrel and 2-oxo-clopidogrel concentrations in plasma. METHODS: The patients were recruited upon acute myocardial infarction diagnosis. They were all tested for...

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PMID: 26695516
DOI: 10.1159/000442712

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ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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