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Article

Modified clopidogrel loading dose according to platelet reactivity monitoring in patients carrying ABCB1 variant alleles in patients with clopidogrel resistance.

European journal of internal medicine - 1 Jan 2012

Wang Xiao-dong, Zhang Dai-fu, Liu Xue-bo, Lai Yan, Qi Wei-gang, Luo Yu, Hu Bo, Yao Yi-an

Abstract excerpt

OBJECTIVES: The aim of the present study was to investigate the impact of a adjusted clopidogrel loading dose (LD) according to platelet reactivity index in carriers of ABCB1 mutant allele undergoing percutaneous coronary intervention (PCI). METHODS: All patients met the inclusion criteria were recruited in the present study. Platelet reactivity was measured using the vasodilator-stimulated phosphoprotein (VASP)...

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Source

Identifiers

PMID: 22153531
DOI: 10.1016/j.ejim.2011.07.016

Genes

ABCB1
VASP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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