Article
Impact of -455G/a polymorphism of the β-fibrinogen gene on platelet aggregation in patients with acute coronary syndrome.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Apr 2014
Sevimli Serdar, Karakoyun Suleyman, Bakirci Eftal Murat, Topcu Selim, Kalkan Kamuran, Borekci Abdurrezzak, Vançelik Serhat
Abstract excerpt
We aimed to investigate the association of aspirin and/or clopidogrel low response with -455G/A polymorphism of β-fibrinogen in patients with acute coronary syndrome (ACS). We enrolled 114 consecutive patients (mean age 61 ± 7, 31 female [27.2%], 83 male [72.8%]) with a first ACS. The diagnostic criteria for ACS were based on current guidelines. The -455 G/A β-fibrinogen polymorphism genotype distribution in the...
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